Dietary reduction of post-prandial hyperglycemia with mulberry tea seen in metabolic syndrome and type-2 diabetes


Dr. S. Banu MD, PhD., DM. Dr. CN Manjunath MD, Jabir NR M’sc, Dr. Narasimha Setty2 MD, Dr. CS Gururaj3 M’sc., Ph.D.

Sri Jayadeva Institute of Cardiovascular Science and Research • Biochemistry • Sri Jayadeva Institute of Cardiovascular Science and Research
Dr.Shaheena Banu, MD, Ph.D.; Dr. CN Manjunath MD DM; Jabir NR MSc • Bangalore

Journal Article: Diabetes and Vascular Disease Research 03/2010; 7:82.


In the management of metabolic syndrome and type 2 diabetes, the role of diet is important. Indian diet contains a large amount of sugar & starches that set off unpredictable blood sugar fluctuations,
increasing the risk of diabetic complications. The aim is to study the effect of Mulberry tea as it is known to contain 1-deoxynojirimycin (DNJ), a potent glycosidase inhibitor and has been
hypothesized to suppress abnormally high postprandial blood glucose levels.

The study is designed in follow-up diabetic patients, 20 diabetics as controls were given plain tea, and 28 patients were given mulberry tea containing DNJ to measure effect based on FBS and

Fasting blood glucose sample was collected, followed by a standard breakfast and one cup of 70ml tea with 1 teaspoon of sugar. The postprandial blood glucose was measured again at 90minutes in all 48 patients.

Fasting valve in control group 178.55635.61 and cases 153.50648.10. After consumption of plain tea and mulberry tea the post-prandial value was287.20656.37 and 210.21658.73 respectively the significance is t54.492; p,0.001** and the effect size are very large (1.31).

Mulberry tea suppresses post-prandial rise of blood glucose levels.